Chemical Name: (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide

Trade Name: Finerenone

CAS No.: 1050477-31-0

Molecular Formula: C21H22N4O3

Molecular Weight: 378.42

Specifications of our Finerenone:

Test Items	Specifications
Appearance	White or off-white powder
Identification	The retention time of test sample major peak complies to reference standard.
	The IR absorption spectrum of the test sample complies to reference standard.
Loss on Drying	Not more than 1.0%
Related Substances	Single impurity: ≤0.1%
	Total impurities: ≤1.0%
Enantiomer	Not more than 0.1%
Residue on Ignition	Not more than 0.1%
Heavy Metals	Not more than 20 ppm
Residual Solvents	Ethanol: ≤5000 ppm
	Toluene: ≤890 ppm
	Tetrahydrofuran: ≤720 ppm
	Acetonitrile: ≤410 ppm
	tert-Butyl methyl ether: ≤5000 ppm
	Ethyl acetate: ≤5000 ppm
Assay(on the anhydrous basis)	98.0% ~ 102.0%

Indications:
For use in adults with chronic kidney disease associated with type 2 diabetes (estimated glomerular filtration rate [eGFR] 25 to <75 mL/min/1.73 m2 with albuminuria) to reduce persistent eGFR decline, end-stage Risk of kidney disease.

Pharmacological Effects:
This drug is a nonsteroidal, selective mineralocorticoid receptor (MR) antagonist. MR is expressed in the kidney, heart, and blood vessels, and finerenone can reduce inflammation and fibrosis mediated by MR overactivation.

Packaging:
100g/bag, 500g/bag, 1kg/bag or according to the specific requirements from customers.

Storage Conditions:
Preserved in unopened original containers in a cool dry place before using; kept away from direct sunlight, heat and moisture.

Shelf Life:
24 months if stored under above mentioned conditions.