Product Name: Acetazolamide

Alias: 2-acetamido-5-sulfamoyl-1,3,4-thiadiazole; 5-acetamido-1,3,4-thiadiazole-2-sulfonamide; 2-ACETAMINO-1,3,4-THIADIAZOLE-5-SULFONAMIDE; N-(5-SULFAMOYL-1,3,4-THIADIAZOL-2-YL)ACETAMIDE; N-(5-SULFAMOYL-1,3,4-THIADIAZOL-2-YL)ETHANAMIDE; N-(5-[AMINOSULFONYL]-1,3,4-THIADIAZOL-2-YL)ACETAMIDE; N-[5-(AMINOSULFONYL)-1,3,4-THIADIOZOL-2-YL]-ACETAMIDE

CAS No.: 59-66-5

EINECS No.: 200-440-5

Molecular Formula: C4H6N4O3S2

Molecular Weight: 222.25

Brief Introduction:
Acetazolamide, whose chemical name is N-(5-SULFAMOYL-1,3,4-THIADIAZOL-2-YL)ACETAMIDE, also called 2-acetamido-5-sulfamoyl-1,3,4-thiadiazole or 5-acetamido-1,3,4-thiadiazole-2-sulfonamide, it is an organic compound with the chemical formula C4H6N4O3S2.

Specifications of our Acetazolamide:

Test Items		Specifications
Description	Characteristic	White acicular crystalline or crystalline powder; odourless
	Solubility	Slightly soluble in boiling water, extremely slightly soluble in water or ethanol, almost insoluble in chloroform or ether, and soluble in ammonia
Identification	Physical and chemical identification 1	Produces a white sediment
	Physical and chemical identification 2	Produces a ethyl acetate aroma
	Infrared Identification	The infrared absorption spectrum of this product should match with that of the working standard (infrared absorption spectrum 9)
pH Value		4.0 ~ 6.0
The clarity of an alkaline solution		The solution should be clarified
Chloride		Not more than 0.014%
Sulphate		Not more than 0.04%
Related Substances		Total impurities shall be: Not more than 1.0%
		The single impurity: Not more than 0.5%
Silver reduction		Consumption of ammonium thiocyanate titrates (0.1mol/L) shall not be less than 4.8 ml
Loss on Drying		Not more than 0.5%
Residue on Ignition		Not more than 0.1%
Heavy Metals		Not more than 20 ppm
Residual Solvents		Glacial acetic acid: Not more than 0.5%
		Acetonitrile: Not more than 0.041%
Assay		98.0% ~ 102.0% (C4H6N4O3S2)
Microbial Limits		Total aerobic bacteria: Not more than 1000CFU/g
		Total molds and yeasts: Not more than 100CFU/g

Applications:
Acetazolamide is a diuretic and carbonic anhydrase inhibitor. After taking it, it inhibits carbonic anhydrase in renal tubular epithelial cells, reducing the formation of H2CO3 and subsequently decreasing the production of H+. Therefore, the exchange of H+ and Na+ is greatly slowed down. As a result, the excretion of HCO3-, Na+, and K+ increases, then the urine output increases. It can also inhibit the aqueous humor secretion process and reduce intraocular pressure.
Acetazolamide can also be used to treat glaucoma, mild cardiac edema, etc.

Packaging:
1kg/bag, 20kg/drum or according to the specific requirements from customers.

Storage Conditions:
Preserved in unopened original containers in a cool dry place before using; kept away from direct sunlight, heat and moisture.

Shelf Life:
36 months if stored under above mentioned conditions.