Product Name: Vildagliptin

Alias: Vidagliptin; (2S)-1-[N-(3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl)glycyl]pyrrolidine-2-carbonitrile; 2-Pyrrolidinecarbonitrile, 1-(((3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)amino)acetyl)-, (2S)-; (-)-(2S)-1-[[(3-Hydroxytricyclo[3.3.1.1[3,7]]dec-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile

CAS No.: 274901-16-5

EINECS No.: 630-410-0

Molecular Formula: C17H25N3O2

Molecular Weight: 303.4

Brief Introduction:

Vildagliptin is a DPP-4 enzyme inhibitor. DPP-4 enzyme inhibitors mainly enhance the effect of incretin by inhibiting DPP-4. DPP-4 enzyme inhibitors can increase the level of endogenous active GLP-1 by 2-3 times, thereby enhancing the sensitivity of β-cells and α-cells to glucose, that is to say, it can increase glucose-stimulated insulin secretion and enhance the inhibitory effect of glucose on glucagon secretion, thereby improving hyperglycemia.

Specifications of our Vildagliptin:

Character		White to yellowish white or grayish white powder
Identification		It exhibits most strongest absorption at the wave numbers of about 3293cm-1, 2915cm-1, 2238cm-1, 1659cm-1, 1407cm-1, 1355cm-1 and 1151cm-1
Purity	Heavy Metals	Not more than 10 ppm
	Related Substances 1	L-Prolinamide: Not more than 0.10%
		AHA: Not more than 0.10%
	Related Substances 2	RRt about 0.6 impurity: Not more than 0.10%
	Related Substances 3	Maximum impurity: Not more than 0.10%
		Total impurities: Not more than 0.50%
	Enantiomer	RRt about 0.78 impurity: Not more than 0.10%
Water		Not more than 0.5%
Residue on Ignition		Not more than 0.1%
Assay		98.5% ~ 101.0%
Foreign Matter Test		Fatal foreign matter: 0
		Critical foreign matter: Not more than 2
		Minor foreign matter: Not more than 5
Residual Solvents 1		2-Butanone: Not more than 5000 ppm
Residual Solvents 2		2-Propanol: Not more than 5000 ppm
		Dichloromethane: Not more than 600 ppm
		Triethylamine: Not more than 5000 ppm

Packaging:
1kg/Aluminum Foil Bag, 20kg/Drum or according to the specific requirements from customers.

Storage Conditions:
Preserved in unopened original containers in a cool dry place before using; kept away from direct sunlight, heat and moisture.

Shelf Life:
24 months if stored under above mentioned conditions.