Product Name: Sermaglutide

Alias: Ozempic; Semaglutide; Ozempic, Rybelsus; GLP-1RA

CAS No.: 910463-68-2

EINECS No.: 203-405-2

Molecular Formula: C187H291N45O59

Specifications of our Sermaglutide (Semaglutide):

Appearance		White or off-white powder
Solubility		Freely soluble in water; Firstly, to add freshly boiled and cooled water to make a clear solution containing 0.15mg of semaglutide in 1ml. Then, to adjust the pH of the solution to 5.5 with 0.05M hydrochloric acid and keep for 30 seconds. Finally, to adjust the pH of the solution to 3.0 and keep 30 seconds. The solution should be turbid in the range of pH 3.0 to 5.5.
Identification	HPLC	As obtained in the Assay, the difference between the retention time of the major peak of the sample solution and the reference solution should be less than 1 minute.
	Peptide Mapping	Peptide mapping of sample solution is similar to that of reference solution.
	N-terminal amino acid sequence	His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu
pH Value		7.0 ~ 8.0
Water Content (K. F)		Not more than 8.0%
Related Substances	Hydrophilic Impurities	Not more than 1.5%
	Hydrophobic Impurities 1	Not more than 1.0%
	Hydrophobic Impurities 2	Not more than 0.2%
	Total Impurities	Not more than 2.0%
High Molecular Weight Proteins		Not more than 0.2%
Residual Solvents	Ethanol	Not more than 0.5%
	Acetonitrile	Not more than 0.041%
	Dichloromethane	Not more than 0.06%
Biological Activity		Should be 0.7U ~ 1.3U per 1mg
Residual Host Cell Protein		Not more than 100ng/mg
Residual Host Cell DNA		Not more than 10ng/mg
Bacterial Endotoxins		Not more than 10EU/mg
Microbial Limits	Total Aerobic Microbial Count	Not more than 100 CFU/g
	Total Yeasts and Moulds Count	Not more than 100 CFU/g
Assay(C187H291N45O59)		Containing Semaglutide 0.76mg ~ 1.00mg per 1mg

Effects & Functions:

1. Immune regulation: Semaglutide can enhance the activity of immune cells, promote the activity of macrophages and lymphocytes, and enhance the body's immunity. It is of great significance in improving the body's immunity and preventing and treating infectious diseases;

2. Antioxidant: Semaglutide can scavenge free radicals in the body, reduce the harm of oxidation, protect the integrity and health of cells, therefore has the effect of protecting the health of cells and organs;

3. Promote growth and development: Semaglutide can stimulate the growth and differentiation of cells, promote human growth and development, and enhance physical fitness;

4. Lower blood sugar: Semaglutide has an insulin-like effect, which can lower blood sugar and prevent and treat diabetes;

5. Lipid-lowering: Semaglutide can reduce the levels of cholesterol and triacylglycerol in the blood, preventing and treating diseases such as hyperlipidemia;

6. Liver protection: Semaglutide can also protect the liver.

Packaging:

1g/Bottle, 3g/Bottle, 5g/Bottle, 10g/Bottle or according to the specific requirements from customers.

Storage Conditions:

For short-term transportation, please keep it at 2-8 degrees Celsius. But please store it in unopened original containers at a temperature of -20±5℃ if based on long-term storage (more than 6 months); protected from direct sunlight, heat and moisture.

Shelf Life:

36 months if stored under above mentioned conditions.