Product Name: Nonapeptide-1

Alias: Melitan; melanostatine; Nonapeptide-1; Melanostatine-5; Melanostatine-5(nonpeptide-1); Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2; Nonapeptide-1, Melanostatine-5, Melanostatine; L-Methionyl-L-prolyl-D-phenylalanyl-L-arginyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valinamide

CAS No.: 158563-45-2

Molecular Formula: C61H87N15O9S

Molecular Weight: 1206.5

Sequence: Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2

Brief Introduction:

Nonapeptide-1 is a biomimetic nonapeptide that can antagonize α-MSH(α-melanocyte stimulating hormone) and thereby inhibit melanin formation. As a bionic peptide, this peptide can antagonize α-MSH and has a very good effect on controlling undesirable skin color and age spots. Clinical studies have shown that it has a good whitening effect on Asians, is non-cytotoxic, and does not affect the function of melanocytes, which is an ideal skin whitening agent.

Specifications of our Nonapeptide-1:

Appearance	White or off-white powder
Molecular Ion Mass	1206.5
Purity (HPLC)	Not less than 99.0%
Acetic Acid Content (HPLC)	Not more than 15.0%
TFA Content (HPLC)	Not more than 0.5%
Water Content (Karl Fischer)	Not more than 8.0%
pH Value (1% Aqueous Solution)	5.5 ~ 7.5
Peptide Content	Not less than 80.0%
Water Solubility	Not less than 100mg per ml

Some Shortcomings of Traditional Whitening and Freckle Removal Raw Materials:

Hydroquinone	It is cytotoxic and can easily cause permanent white spots.
Arbutin	It is photosensitive and not suitable for use during the day.
Kojic Acid	Easy to oxidize and irritating to skin.

Characteristics that New Whitening Raw Materials Should Have:

♔ Can inhibit tyrosinase activity;

♔ Not toxic or mutagenic;

♔ Has proven clinical efficacy;

♔ Good stability in formulation;

♔ Protects the stability of the formula.

Recommended Dosage:

1% ~ 8%

Packaging:

1g/bottle, 3g/bottle, 5g/bottle, 10g/bottle, 30g/bottle, 50g/bottle, 100g/bottle or according to the specific requirements from customers.

Storage Conditions:

Palmitoyl Pentapeptide-4 should be stored in unopened original containers in a cool dry place before using; kept away from direct sunlight, heat and moisture; preserved at 2℃ to 8℃ for short-term storage, -20℃±5℃ for long-term storage.

Shelf Life:

24 months if stored under above mentioned conditions.