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Medetomidine Hydrochloride

Release time:2025-03-19

1. Product Name: Medetomidine hydrochloride

2. Synonyms: Medetomidine HCL; 4-[1-(2,3-DIMETHYLPHENYL)ETHYL]-1H-IMIDAZOLE HYDROCHLORIDE; 4-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole hydrochloride; (r)-4-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole hydrochloride; 4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole Monohydrochloride; 1H-Imidazole, 4-1-(2,3-dimethylphenyl)ethyl-, monohydrochloride

3. CAS No.: 86347-15-1

4. EINECS No.: 1308068-626-2

5. Molecular Formula: C13H17ClN2

6. Molecular Weight: 236.74


7. Brief Introduction:

Medetomidine hydrochloride, the CAS number is 86347-15-1, the molecular formula is C13H17ClN2, the molecular weight is 236.74, the melting point is between 164°C and 166°C. Medetomidine hydrochloride is an α2-adrenergic receptor agonist, mainly used for sedation, analgesia and anesthesia assistance in the veterinary field.


8. Mechanism of Action:

By activating central and peripheral α2-adrenergic receptors, inhibiting sympathetic nerve activity, it produces:
♔ Sedation: Reduces animal anxiety and activity.
♔ Analgesia: Relieves pain.
♔ Muscle Relaxation: Assists in examination and surgery.


9. Specifications of our Medetomidine Hydrochloride(Medetomidine HCL):

Appearance
Off-white to white powder
Identification
Chemical identification
Infrared spectrometry
Chloride identification
pH Value
3.5 ~ 4.5
Clarity and Color of Solution
Clear and colorless, if there is the turbidity and color, less than turbidity-1 and yellow-1
Residue on Ignition
Not more than 0.1%
Related Substances
Max single impurity
Not more than 0.2%
Total impurities
Not more than 1.0%
Heavy Metals
Not more than 10 ppm
Loss on Drying
Not more than 1.0%
Residual Solvents
Methanol
Not more than 0.3%
Acetone
Not more than 0.5%
Dichloromethane
Not more than 0.06%
Assay (on the anhydrous basis)
Not less than 99.0%


10. Main Uses:

▲ Veterinary Anesthesia: Often used in combination with drugs such as Ketamine to reduce the amount of anesthetics required.

▲ Preoperative Sedation: Facilitates intubation or operation.

Diagnosis/Examination: Keep animals quiet during imaging examinations.

Wildlife Management: Used to safely capture large or dangerous animals.


11. Features and Advantages:

★ Fast Onset: Usually takes effect in 5-15 minutes.

★ Reversibility: The effect can be reversed by α2 receptor antagonists (such as Atipamezole).

★ High Safety: Well tolerated by most animals at appropriate doses.


12. Drug Form:

※ Usually injection (intravenous or intramuscular), specific usage needs to be guided by a veterinarian.


13. Packaging:

10g/Bag, 20g/Bag, 50g/Bag, 100g/Bag, 500g/Bag, 1kg/Bag or according to the specific requirements from customers.


14. Storage Conditions:

Preserved in unopened original containers in a cool dry place before using; kept away from direct sunlight, heat and moisture.


15. Shelf Life:

24 months from the date of manufacturing when stored under the above conditions.