Product Name: Calcium L-5-Methyltetrahydrofolate

Alias: Levomefolate Calcium; L-Methylfolate calcium salt; Levomefolic acid; (6S)-5-Methyltetrahydrofolic acid; LMSR; N-(4-((((6S)-2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid; L-5-MTHF-Ca; 5-MTHF

Molecular Formula:C20H27CaN7O6

Molecular Weight: 501.56

CAS No.: 151533-22-1

EINECS: 691-636-3

Melting Point:＞300℃

Description: The calcium salt of L-5-methyltetrahydrofolate belongs to the folic acid family vitamins(vitamin B9, folic acid), which is a coenzyme form of folic acid. l-5-methyltetrahydrofolate calcium(5-mthf), is the naturally occurring salt-forming methyl derivative form of folic acid, 5-mthf is also known as L-methylfolate, it is the most biologically active and functional form of folic acid form, which is more easily absorbed than regular folic acid.

Items	Specifications
Appearance	White to light yellow crystalline powder
Identification	HPLC: The retention time of the major peak in the chroma-togram of the sample solution corresponds to that of the reference standard in the assay test IR: In accordance with standard atlas Calcium: Conformance to Requirements
Particle Size	Not less than 80% pass through 80 mesh Not more than 3% pass through 270 mesh
Crystal Type	C Crystal
Calcium L-5-Methyltetrahydrofolate	95.0%-102.0%(On Dried Basis)
L-5-Methyltetrahydrofolate	Not less than 85.0%(On Dried Basis)
Chloride	Not more than 0.5%
D-5-Methylfolate	Not more than 1.0%
Boron	Not more than 50ug/g
Platinum	Not more than 10ug/g
Arsenic	Not more than 1.5ug/g
Cadmium	Not more than 0.5ug/g
Lead	Not more than 1.0ug/g
Mercury	Not more than 1.5ug/g
4-aminobenzoyl-glutamic acid	Not more than 0.5%
4a-Hydroxy-5-methyltetrahydrofolic acid	Not more than 1.0%
(6R)-Mefox   (6S)-Mefox	Not more than 1.0%(6R+6S)
Tetrahydrofolic acid	Not more than 0.5%
7,8 dihydrofolic acid	Not more than 0.5%
Folic Acid	Not more than 0.5%
5,10-methyltetrahydrofolic acid	Not more than 0.5%
5-methyltetrahydropteroic acid	Not more than 0.5%
Dimethyltetrahydrofolic acid	Not more than 0.15%
Individual unknown impurity	Not more than 0.10%
Total impurities	Not more than 2.5%
Ethanol	Not more than 5000ppm
Acetone	Not more than 5000ppm
Isopropyl alcohol	Not more than 5000ppm
Water Content(K. Fischer)	6.0%-17.0%
Calcium(On the anhydrous and solvent-free basis)	7.0%-8.5%
Total Plate Count	Less than 1000CFU/g
Moulds & Yeasts	Less than 100CFU/g
Bile resistance of gram-negative bacteria	Less than 100CFU/g
E.coli	Not Detected/g
Staphylococcus aureus	Not Detected/g
Salmonella	Not Detected/10g

Packaging: Double PE bags, one Aluminum foil bag, Carton or customized containers.

Shelf Life: 24 months after manufacturing date.

Storage Condition: Stored in a cool and dry place, in a tight container.