Product Name: Mazdutide

CAS No.: 2259884-03-0

Molecular Formula: C210H322N46O67

Molecular Weight: 4563.06

Forms of Supplying: ① Raw Powder; ② Lyophilized Powder: 5mg/Vial, 10mg/Vial.

Brief Introduction:

Mazdutide is a novel dual agonist of GLP-1 (glucagon-like peptide-1) and GCG (glucagon) receptors developed by China Innovent Biologics and Eli Lilly, mainly used for the treatment of obesity and type 2 diabetes.

Sequence:

H-His-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Glu-Lys-Lys-Ala-Lys-(AEEA-AEEA-γ-Glu-diacid-C20)-Glu-Phe-Val-Glu-Trp-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-NH2

Mechanism of Action:

♔ Dual-target Stimulation: Activate GLP-1 and GCG receptors simultaneously, exerting multiple metabolic regulatory effects:

• GLP-1 receptor: promote insulin secretion, suppress appetite, and delay gastric emptying.
• GCG receptor: increase energy consumption and promote fat decomposition.

♔ Synergistic Weight Loss: The dual mechanism can reduce calorie intake and accelerate fat metabolism, and the weight loss effect may be better than single-target drugs.

Indications:

★ Obesity:

Clinical trials have shown significant weight loss effects (e.g., the average weight loss in the high-dose group was more than 15% in 48 weeks).

★ Type 2 diabetes:

Auxiliary treatment by improving insulin sensitivity and blood sugar control.

Usage and Features:

▲ Dosage: Subcutaneous injection once a week, highly convenient.
▲ Potential Advantages:
- Weight loss effect is nearly twice that of GLP-1 single-target drugs such as Semaglutide.
- May improve liver fat deposition and metabolic syndrome.

Differences from Cagrilintide:

1) Target:

Mazdutide is a GLP-1/GCG dual agonist, but Cagrilintide is an amylin analog.

2) Indications:

Both are used for obesity, but Mazdutide focuses more on comprehensive metabolic regulation, while Cagrilintide focuses on appetite suppression.

Specifications of our Mazdutide:

Appearance	White to off-white powder
Purity (HPLC)	Not less than 98.0%
Sodium	Not more than 5.0%
Water Content (Karl Fischer)	N/A
MS	Consistent

Packaging:

① Raw Powder:
1g/Bottle, 2g/Bottle, 3g/Bottle, 5g/Bottle or according to the specific requirements from customers.
② Lyophilized Powder:
10 Vials per Box.

Minimum Order Quantity (MOQ):

① Raw Powder: 1 gram.
② Lyophilized Powder: One Box (10 Vials).

Payment Methods:

Storage Conditions:

① Raw Powder:
Stored in a cool dry place away from sunlight and moisture.
② Lyophilized Powder:
Preserved in air tight containers, protected from light (Recommended temperature: -25℃ ~ -15℃).

Shelf Life:

24 months from the date of manufacturing when stored under the above mentioned conditions.